AOSpine Masters Series Volume 1: Metastatic Spinal Tumors by Ziya L. Gokaslan, Stefano Boriani, Charles G Fisher, Luiz

By Ziya L. Gokaslan, Stefano Boriani, Charles G Fisher, Luiz Roberto Gomes Vialle

This first quantity within the AOSpine Masters sequence integrates the services of oncologists and radiology interventionalists with that of grasp backbone surgeons, all of whom are actively thinking about the care of sufferers with metastatic backbone tumors. The booklet offers professional suggestions to assist clinicians make the correct therapy judgements and supply the easiest deal with their sufferers. bankruptcy issues variety from review and decision-making rules to a spectrum of non-operative and operative therapies which have been quickly evolving during the last decade.

Key Features:

  • Editors are internationally-recognized experts on metastatic backbone tumors
  • Includes contributions from key opinion leaders operating in backbone oncology
  • Synthesizes the easiest to be had proof and consensus specialist recommendation on metastatic backbone tumors, resulting in optimum medical innovations
  • Each bankruptcy comprises medical pearls, tips about hassle avoidance, and most sensible five must-read references

The AOSpine Masters sequence, a co-publication of Thieme and the AOSpine starting place, addresses present medical concerns wherein overseas masters of backbone proportion their services and proposals on a selected subject. The target of the sequence is to give a contribution to an evolving, dynamic version of an evidence-based medication method of backbone care.

All neurosurgeons, orthopedic surgeons, neuro-oncologists, and orthopedic oncologists focusing on backbone, besides citizens and fellows in those parts, will locate this booklet to be a great advisor that they are going to seek advice usually of their remedy of sufferers with metastatic backbone tumors.

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Example text

16 There were 31 (15%) acute and 24 (12%) late esophageal toxicities during the median follow-up interval of 12 months. 8%) patients. 11 cc, and 0 cc, respectively. They also note the maximum point dose should be kept below 22 Gy. Importantly, the seven patients who developed grade 4 or higher toxicities either had radiation recall reactions after chemotherapy with doxorubicin or gemcitabine, or iatrogenic esophageal manipulation, such as biopsy, dilatation, and stent placement. 5 Gy × 4 fractions, and 5 to 10 Gy × 5 fractions.

Rose PS, Laufer I, Boland PJ, et al. Risk of fracture after single fraction image-guided intensity-modulated radiation therapy to spinal metastases. Boehling NS, Grosshans DR, Allen PK, et al. Vertebral compression fracture risk after stereotactic body radiotherapy for spinal metastases. Chow E, Harris K, Fan G, Tsao M, Sze WM. Palliative radiotherapy trials for bone metastases: a systematic review. J Clin Oncol 2007;25:1423–1436 PubMed 18. Cunha MV, Al-Omair A, Atenafu EG, et al. Vertebral compression fracture (VCF) after spine stereotactic body radiation therapy (SBRT): analysis of predictive factors.

Esophageal Toxicity The esophagus is located immediately in front of the spinal column, especially for the thoracic segments, and is susceptible to injury by ablative doses of radiation delivered to the spine. There is limited literature specific to esophageal toxicity from SABR. 16 There were 31 (15%) acute and 24 (12%) late esophageal toxicities during the median follow-up interval of 12 months. 8%) patients. 11 cc, and 0 cc, respectively. They also note the maximum point dose should be kept below 22 Gy.

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